Translational digital biomarkers are objective, quantifiable physiological and behavioral data that are collected and measured by means of digital technologies. They are clinically relevant and translational between preclinical studies and the clinic. These biomarkers have the potential to help reduce the number of laboratory animals needed for biomedical research and refine their lives during necessary projects.

NA3RsC Translational Digital Biomarkers Initiatve was established as a collaboration among early-stage users, including scientists and stakeholders and commercially available digital biomarker technology providers to establish an improved understanding of the value and to facilitate the optimal implementation of digital biomarker technologies in research. The initiative will engage end-users and those interested in learning more about how these technologies can be used to promote the 3Rs.

Our planned deliverables are:

- Create a virtual knowledge exchange where scientists & regulatory bodies can access information about translational digital biomarkers
- Create a database by sharing summarized scientific data (precompetitive or blinded) collected from these technologies that can be used in practice to support data-driven refinements to animal welfare
- Promote & coordinate interactions and discussions among end-users and technology providers to share learnings, discuss and identify opportunities for animal welfare refinements
- Organize a translational digital biomarkers conference to bring technology providers & end-users together

For more information and to join our TDB initiative, click here.